The Command to Follow the Revelation
Allah commands His Messenger and those who followed his path,
اتَّبِعْ مَآ أُوحِىَ إِلَيْكَ مِن رَّبِّكَ
(Follow what has been inspired to you from your Lord,) meaning, follow it, obey it and act according to it. What has been revealed to you from your Lord is the Truth, no doubt, and there is no deity worthy of worship except Him,
وَأَعْرِضْ عَنِ الْمُشْرِكِينَ
(and turn aside from the idolators) meaning, forgive them, be forbearing and endure their harm until Allah brings relief to you, supports you and makes you triumphant over them. Know -- O Muhammad -- that there is a wisdom behind misleading the idolators, and that had Allah willed, He would have directed all people to guidance,
وَلَوْ شَآءَ اللَّهُ مَآ أَشْرَكُواْ
(Had Allah willed, they would not have taken others besides Him in worship.) Allah's is the perfect will and wisdom in all decrees and decisions, and He is never questioned about what He does, while they all will be questioned. Allah's statement,
وَمَا جَعَلْنَـكَ عَلَيْهِمْ حَفِيظاً
(And We have not made you Hafiz over them.) means, a watcher who observes their statements and deeds,
وَمَآ أَنتَ عَلَيْهِم بِوَكِيلٍ
(Nor are you set over them to dispose of their affairs. ) or to control their provision. Rather, your only job is to convey, just as Allah said,
فَذَكِّرْ إِنَّمَآ أَنتَ مُذَكِّرٌ - لَّسْتَ عَلَيْهِم بِمُسَيْطِرٍ
(So remind them, you are only one who reminds. You are not a dictator over them.) 88:21-22 and,
فَإِنَّمَا عَلَيْكَ الْبَلَـغُ وَعَلَيْنَا الْحِسَابُ
(Your duty is only to convey and on Us is the reckoning.) 13:40
Ma'arif al-Qur'an
Mufti Muhammad Shafi
The reason for this has been given in the fifth verse (107). There it has been said: If Allah Ta` ala had willed - in consideration of His own creational imperative - that the whole human race should become Muslim in faith, then, it would have become impossible for them to associate partners in the Divinity of Allah (Shirk). But, it was because of their misdeeds that Allah willed that they be punished. So, He created the necessary conditions for that end. Now, how could he make them Muslims under these circumstances? In fact, why should he worry about what they choose to do with their lives? Allah has not made him to stand guard over what they do, nor has he been authorized by Allah to bring punishment on them for their misdeeds. Therefore, he should not have any anxiety on account of what they do to themselves or for themselves.
There are some who have the urge to acquire knowledge and learn; who are in search of Truth. There are others who have acquired wealth and power and consider themselves successful to the point of feeling that there is nothing lacking in them which needs to be compensated for. When the call of Truth is given, it is mostly the former kind of people who accept it, unlike the latter who do not attach any significance to it. They never give it any serious thought, and therefore its importance does not become clear to them. The call of Truth provides answers for those who earnestly go in quest of the truth, and gives those who are not so inclined, a logical conclusion to their arguments. With regard to the former, the aim is to enable them to accept the truth; as for the others, it is meant to make them concede that at least the divine message had been conveyed to them in full.
Uthmani text of the Madinah mushaf (King Fahd Complex). Translation: Saheeh International. Tafsir via Quran.com.